English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID1sjh  sequence information (FASTA format)   
RELATED PDB ID1klu, 1pyw, 1sje
DescriptorHLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1-1 beta chain, GAG polyprotein [Contains: Core proteins P17, P24, P2, P7, P1, P6], Enterotoxin type C-3
TitleHLA-DR1 complexed with a 13 residue HIV capsid peptide
Functional KeywordsMHC class II, Major histocompatibility protein complex, HLA-DR1, HIV-1, capsid, superantigen, antigen, peptide, gag, IMMUNE SYSTEM
Biological sourceHomo sapiens (human) ,Staphylococcus aureus (the details in Structural Details Page)
Cellular location [UNP - P01903] Membrane; Single-pass type I membrane protein
[UNP - P12495] Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential)
[UNP - P0A0L5] Secreted
Organ source [UNP - P01903] Blood, and Colon
[UNP - P01903] B-cell
[UNP - P01903] Blood
[UNP - P04229] Cerebellum
Total number of polymer chains4
Total molecular weight72092.5 (the details in Structural Details Page)
AuthorsZavala-Ruiz, Z. , Strug, I. , Walker, B.D. , Norris, P.J. , Stern, L.J. (deposition date : 2004-03-03, release date : 2004-08-17)
Primary citationZavala-Ruiz, Z. , Strug, I. , Walker, B.D. , Norris, P.J. , Stern, L.J.
A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.
Proc.Natl.Acad.Sci.Usa, 101:13279 - 13284, 2004.(PubMed : 15331779)  (DOI: 10.1073/pnas.0403371101)
Experimental methodX-RAY DIFFRACTION ( 2.25[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01903, P04229, P12495, P0A0L5 ) , eF-site , PISA