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MineSummary [1u5a]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID1u5a  sequence information (FASTA format)   
RELATED PDB ID1u40, 1u4s
DescriptorL-lactate dehydrogenase (E.C.1.1.1.27)
TitlePlasmodium falciparum lactate dehydrogenase complexed with 3,5-dihydroxy-2-naphthoic acid
Functional KeywordsProtein-ligand complex, OXIDOREDUCTASE
Biological sourcePlasmodium falciparum (malaria parasite P. falciparum)
Total number of polymer chains1
Total molecular weight35050.9 (the details in Structural Details Page)
AuthorsConners, R. , Cameron, A. , Read, J. , Schambach, F. , Sessions, R.B. , Brady, R.L. (deposition date : 2004-07-27, release date : 2005-06-21)
Primary citationConners, R. , Schambach, F. , Read, J. , Cameron, A. , Sessions, R.B. , Vivas, L. , Easton, A. , Croft, S.L. , Brady, R.L.
Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase.
Mol.Biochem.Parasitol., 142:137 - 148, 2005.(PubMed : 15978953)  (DOI: 10.1016/j.molbiopara.2005.03.015)
Experimental methodX-RAY DIFFRACTION ( 1.80[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q27743 ) , eF-site , KEGG ( EC 1.1.1.27 ) , PISA