English Statistics Help FAQ Contact Us
Download >>
Links

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

MineSummary [2jjs]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID2jjs  sequence information (FASTA format)   
RELATED PDB ID2vsc, 2jjt, 2uv3
DescriptorTYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, LEUKOCYTE SURFACE ANTIGEN CD47
TitleSTRUCTURE OF HUMAN CD47 IN COMPLEX WITH HUMAN SIGNAL REGULATORY PROTEIN (SIRP) ALPHA
Functional KeywordsSIGNAL REGULATORY PROTEIN ALPHA, IMMUNOGLOBULIN SUPERFAMILY, TRANSMEMBRANE, PHOSPHOPROTEIN, PAIRED RECEPTOR, POLYMORPHISM, GLYCOPROTEIN, CELL ADHESION, PYRROLIDONE CARBOXYLIC ACID, ALTERNATIVE SPLICING, IMMUNOGLOBULIN DOMAIN, SIRP, CD47, SIRPA, MEMBRANE, SH3-BINDING
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains4
Total molecular weight60487.6 (the details in Structural Details Page)
AuthorsHatherley, D. , Graham, S.C. , Turner, J. , Harlos, K. , Stuart, D.I. , Barclay, A.N. (deposition date : 2008-04-22, release date : 2008-08-05)
Primary citationHatherley, D. , Graham, S.C. , Turner, J. , Harlos, K. , Stuart, D.I. , Barclay, A.N.
Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31:266 - 277, 2008.(PubMed : 18657508)  (DOI: 10.1016/j.molcel.2008.05.026)
Experimental methodX-RAY DIFFRACTION ( 1.85[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P78324, Q08722 ) , eF-site , PISA