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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1q3w  sequence information (FASTA format)   
RELATED PDB ID1pyx, 1q3d, 1q41
DescriptorGlycogen synthase kinase-3 beta (E.C.2.7.1.37)
TitleGSK-3 Beta complexed with Alsterpaullone
Functional KeywordsKINASE, INSULIN PATHWAY, ALSTERPAULLONE, TRANSFERASE
Biological sourceHomo sapiens (human)
Organ source [UNP - P49841] Eye, and Placenta
[UNP - P49841] Epithelium
[UNP - P49841] Platelet
Total number of polymer chains2
Total molecular weight94750.6 (the details in Structural Details Page)
AuthorsBertrand, J.A. , Thieffine, S. , Vulpetti, A. , Cristiani, C. , Valsasina, B. , Knapp, S. , Kalisz, H.M. , Flocco, M. (deposition date : 2003-08-01, release date : 2003-10-21)
Primary citationBertrand, J.A. , Thieffine, S. , Vulpetti, A. , Cristiani, C. , Valsasina, B. , Knapp, S. , Kalisz, H.M. , Flocco, M.
Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors
J. Mol. Biol., 333:393 - 407, 2003.(PubMed : 14529625)  (DOI: 10.1016/j.jmb.2003.08.031)
Experimental methodX-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P49841 ) , eF-site , KEGG ( EC 2.7.1.37 ) , PISA