PDB ID 1q5o sequence information (FASTA format)
RELATED PDB ID 1q3e , 1q43
Descriptor Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Title HCN2J 443-645 in the presence of cAMP, selenomethionine derivative
Functional Keywords CNBD, C-LINKER, PACEMAKER, HCN, HCN2, CHANNEL, CYCLIC NUCLEOTIDE, CAP, PKA, cAMP, ION CHANNEL, LIGAND, Transport protein
Biological source Mus musculus
(house mouse)
Cellular location
[UNP - O88703 ]
Membrane; Multi-pass membrane protein
Organ source brain
Total number of polymer chains 1
Total molecular weight 24897.3 (the details in Structural Details Page )
Authors Zagotta, W.N. , Olivier, N.B. , Black, K.D. , Young, E.C. , Olson, R. , Gouaux, J.E.
(deposition date : 2003-08-08, release date : 2003-09-09)
Primary citation Zagotta, W.N. , Olivier, N.B. , Black, K.D. , Young, E.C. , Olson, R. , Gouaux, E. Structural basis for modulation and agonist specificity of HCN pacemaker channels
Nature ,
425:200 - 205, 2003.(PubMed : 12968185) (DOI: 10.1038/nature01922)
Experimental method X-RAY DIFFRACTION ( 2.3[Å] )
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