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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID1qyv  sequence information (FASTA format)   
RELATED PDB ID1bsv, 1fdu, 1jtv, 1qyw, 1qyx
DescriptorEstradiol 17 beta-dehydrogenase 1 (E.C.1.1.1.62)
TitleCrystal structure of human estrogenic 17beta-hydroxysteroid dehydrogenase complex with NADP
Functional Keywords17bHSD1-cofactor complex, OXIDOREDUCTASE
Biological sourceHomo sapiens (human)
Cellular location [UNP - P14061] Cytoplasm
Organ source [UNP - P14061] Placenta
[UNP - P14061] Brain
Total number of polymer chains1
Total molecular weight35723.6 (the details in Structural Details Page)
AuthorsShi, R. , Lin, S.X. (deposition date : 2003-09-12, release date : 2004-08-03)
Primary citationShi, R. , Lin, S.X.
Cofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientation.
J.Biol.Chem., 279:16778 - 16785, 2004.(PubMed : 14966133)  (DOI: 10.1074/jbc.M313156200)
Experimental methodX-RAY DIFFRACTION ( 1.81[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P14061 ) , eF-site , KEGG ( EC 1.1.1.62 ) , PISA