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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID1r1o  sequence information (FASTA format)   
RELATED PDB ID1d3v, 1hq5
DescriptorArginase 1 (E.C.3.5.3.1)
TitleAmino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase
Functional Keywordsarginase, hydrolase, sulfonamides, transition-state analogue
Biological sourceRattus norvegicus (Norway rat)
Cellular location [UNP - P07824] Cytoplasm
Organ source [UNP - P07824] Liver
Total number of polymer chains3
Total molecular weight106072.5 (the details in Structural Details Page)
AuthorsCama, E. , Shin, H. , Christianson, D.W. (deposition date : 2003-09-24, release date : 2003-10-28)
Primary citationCama, E. , Shin, H. , Christianson, D.W.
Design of Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase
J. Am. Chem. Soc., 125:13052 - 13057, 2003.(PubMed : 14570477)  (DOI: 10.1021/ja036365b)
Experimental methodX-RAY DIFFRACTION ( 2.8[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P07824 ) , eF-site , KEGG ( EC 3.5.3.1 ) , PISA