PDB ID 1r9o sequence information (FASTA format)
RELATED PDB ID 1n6b , 1og5 , 1po5 , 1pq2 , 1nr6
Descriptor Cytochrome P450 2C9 (E.C.1.14.14.1)
Title Crystal Structure of P4502C9 with Flurbiprofen bound
Functional Keywords P450, monooxygenase, drug metabolizing enzyme, oxidoreductase, heme
Biological source Homo sapiens
(human)
Cellular location
[UNP - P11712 ]
Endoplasmic reticulum membrane; Peripheral membrane protein
Organ source
[UNP - P11712 ]
Liver
Total number of polymer chains 1
Total molecular weight 55276.4 (the details in Structural Details Page )
Authors Wester, M.R. , Yano, J.K. , Schoch, G.A. , Griffin, K.J. , Stout, C.D. , Johnson, E.F.
(deposition date : 2003-10-30, release date : 2004-06-15)
Primary citation Wester, M.R. , Yano, J.K. , Schoch, G.A. , Yang, C. , Griffin, K.J. , Stout, C.D. , Johnson, E.F. The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0 A Resolution
J.Biol.Chem. ,
279:35630 - 35637, 2004.(PubMed : 15181000) (DOI: 10.1074/jbc.M405427200)
Experimental method X-RAY DIFFRACTION ( 2.0[Å] )
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