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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1r9o  sequence information (FASTA format)   
RELATED PDB ID1n6b, 1og5, 1po5, 1pq2, 1nr6
DescriptorCytochrome P450 2C9 (E.C.1.14.14.1)
TitleCrystal Structure of P4502C9 with Flurbiprofen bound
Functional KeywordsP450, monooxygenase, drug metabolizing enzyme, oxidoreductase, heme
Biological sourceHomo sapiens (human)
Cellular location [UNP - P11712] Endoplasmic reticulum membrane; Peripheral membrane protein
Organ source [UNP - P11712] Liver
Total number of polymer chains1
Total molecular weight55276.4 (the details in Structural Details Page)
AuthorsWester, M.R. , Yano, J.K. , Schoch, G.A. , Griffin, K.J. , Stout, C.D. , Johnson, E.F. (deposition date : 2003-10-30, release date : 2004-06-15)
Primary citationWester, M.R. , Yano, J.K. , Schoch, G.A. , Yang, C. , Griffin, K.J. , Stout, C.D. , Johnson, E.F.
The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0 A Resolution
J.Biol.Chem., 279:35630 - 35637, 2004.(PubMed : 15181000)  (DOI: 10.1074/jbc.M405427200)
Experimental methodX-RAY DIFFRACTION ( 2.0[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P11712 ) , eF-site , KEGG ( EC 1.14.14.1 ) , PISA