PDB ID 1rkh sequence information (FASTA format)
RELATED PDB ID 1rjk , 1rk3 , 1rkg
Descriptor Vitamin D3 receptor, Peroxisome proliferator-activated receptor binding protein
Title crystal structure of the rat vitamin D receptor ligand binding domain complexed with 2AM20R and a synthetic peptide containing the NR2 box of DRIP 205
Functional Keywords nuclear receptor-ligand complex, nuclear receptor-coactivator interactions, hormone/growth factor receptor COMPLEX
Biological source Rattus norvegicus
(Norway rat)
Cellular location
[UNP - P13053 ]
Nucleus
Organ source
[UNP - P13053 ]
Kidney
[UNP - Q15648 ]
Heart
[UNP - Q15648 ]
Colon, and Testis
[UNP - Q15648 ]
Cervix carcinoma
[UNP - Q15648 ]
Epithelium
Total number of polymer chains 2
Total molecular weight 34973.6 (the details in Structural Details Page )
Authors Vanhooke, J.L. , Benning, M.M. , Bauer, C.B. , Pike, J.W. , F DeLuca, H.
(deposition date : 2003-11-21, release date : 2004-04-13)
Primary citation Vanhooke, J.L. , Benning, M.M. , Bauer, C.B. , Pike, J.W. , DeLuca, H.F. Molecular Structure of the Rat Vitamin D Receptor Ligand Binding Domain Complexed with 2-Carbon-Substituted Vitamin D(3) Hormone Analogues and a LXXLL-Containing Coactivator Peptide
Biochemistry ,
43:4101 - 4110, 2004.(PubMed : 15065852) (DOI: 10.1021/bi036056y)
Experimental method X-RAY DIFFRACTION ( 2.28[Å] )
Other Database Information