PDB ID 1v1m sequence information (FASTA format)
RELATED PDB ID 1dtw , 1ols , 1olu , 1olx , 1v11 , 1v16 , 1v1r
Descriptor 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT (E.C.1.2.4.4), 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT (E.C.1.2.4.4)
Title CROSSTALK BETWEEN COFACTOR BINDING AND THE PHOSPHORYLATION LOOP CONFORMATION IN THE BCKD MACHINE
Functional Keywords OXIDOREDUCTASE, KETOACID DEHYDROGENASE, BRANCHED-CHAIN, MULTI-ENZYME COMPLEX, ACYLATION, OXIDATIVE DECARBOXYLATION MAPLE SYRUP URINE DISEASE, THIAMINE DIPHOSPHATE, PHOSPHORYLATION, FLAVOPROTEIN
Biological source HOMO SAPIENS
(HUMAN)
Cellular location
[UNP - P12694 ]
Mitochondrion matrix
Organ source
[UNP - P12694 ]
Bone marrow, and LungUNP - P12694 ]
LiverUNP - P12694 ]
EpitheliumUNP - P12694 ]
PlateletUNP - P21953 ]
PlacentaUNP - P21953 ]
Eye
Total number of polymer chains 2
Total molecular weight 84407.4 (the details in Structural Details Page )
Authors Li, J. , Wynn, R.M. , Machius, M. , Chuang, J.L. , Karthikeyan, S. , Tomchick, D.R. , Chuang, D.T.
(deposition date : 2004-04-20, release date : 2004-06-03)
Primary citation Li, J. , Wynn, R.M. , Machius, M. , Chuang, J.L. , Karthikeyan, S. , Tomchick, D.R. , Chuang, D.T.J.Biol.Chem. ,
279:32968 - , 2004.(PubMed : 15166214) (DOI: 10.1074/JBC.M403611200)
Experimental method X-RAY DIFFRACTION ( 2.00[Å] )
Other Database Information
