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Summary [1t1y]

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PDB ID or Keywordsequenceauthor name

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<Asymmetric unit> = <Biological unit> More images... View in 3D molecule viewer ( jV3 / Jmol ) *1

PDB ID 1t1y  sequence information (FASTA format)    RELATED PDB ID 1s8d, 1t1w, 1t1x, 1t1z, 1t20, 1t21, 1t22 Descriptor HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, GAG PEPTIDE Title Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-5V Functional Keywords CTL, CYTOTOXIC T LYMPHOCYTES, HIV, HUMAN IMMUNODEFICIENCY VIRUS, MHC, MAJOR HISTOCOMPATIBILITY COMPLEX, PMHC, PEPTIDE MHC COMPLEX, RMSD, ROOT-MEAN-SQUARED DEVIATION, SIV, SIMIAN IMMUNODEFICIENCY VIRUS, TCR, T-CELL RECEPTOR, IMMUNE SYSTEM Biological source Homo sapiens (human) Cellular location [UNP - P01892] Membrane; Single-pass type I membrane protein [UNP - P61769] Secreted Organ source [UNP - P01892] Blood [UNP - P01892] Platelet [UNP - P61769] Peripheral blood [UNP - P61769] Dendritic cell [UNP - P61769] Leukemia [UNP - P61769] Trachea [UNP - P61769] Eye, and Skin [UNP - P61769] Urine Total number of polymer chains 3 Total molecular weight 44581.9 (the details in Structural Details Page) Authors Martinez-Hackert, E. , Anikeeva, N. , Kalams, S.A. , Walker, B.D. , Hendrickson, W.A. , Sykulev, Y. (deposition date : 2004-04-19, release date : 2005-09-06) Primary citation Martinez-Hackert, E. , Anikeeva, N. , Kalams, S.A. , Walker, B.D. , Hendrickson, W.A. , Sykulev, Y. Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem., 281:20205 - 20212, 2006.(PubMed : 16702212)  (DOI: 10.1074/jbc.M601934200) Experimental method X-RAY DIFFRACTION ( 2.00[Å] ) Other Database Information EM Navigator , Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01892, P61769 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS

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