PDB ID 1t64 sequence information (FASTA format)
RELATED PDB ID 1t67
Descriptor Histone deacetylase 8
Title Crystal Structure of human HDAC8 complexed with Trichostatin A
Functional Keywords Histone deacetylase, zinc hydrolase
Biological source Homo sapiens
(human)
Cellular location
[UNP - Q9BY41 ]
Nucleus
Organ source
[UNP - Q9BY41 ]
KidneyUNP - Q9BY41 ]
UterusUNP - Q9BY41 ]
HeartUNP - Q9BY41 ]
Pheochromocytoma
Total number of polymer chains 2
Total molecular weight 85198.6 (the details in Structural Details Page )
Authors Somoza, J.R. , Skene, R.J. , Katz, B.A. , Mol, C. , Ho, J.D. , Jennings, A.J. , Luong, C. , Arvai, A. , Buggy, J.J. , Chi, E. , Tang, J. , Sang, B.-C. , Verner, E. , Wynands, R. , Leahy, E.M. , Dougan, D.R. , Snell, G. , Navre, M. , Knuth, M.W. , Swanson, R.V. , McRee, D.E. , Tari, L.W.
(deposition date : 2004-05-05, release date : 2004-07-27)
Primary citation Somoza, J.R. , Skene, R.J. , Katz, B.A. , Mol, C. , Ho, J.D. , Jennings, A.J. , Luong, C. , Arvai, A. , Buggy, J.J. , Chi, E. , Tang, J. , Sang, B.-C. , Verner, E. , Wynands, R. , Leahy, E.M. , Dougan, D.R. , Snell, G. , Navre, M. , Knuth, M.W. , Swanson, R.V. , McRee, D.E. , Tari, L.W.Structure ,
12:1325 - 1334, 2004.(PubMed : 15242608) (DOI: 10.1016/j.str.2004.04.012)
Experimental method X-RAY DIFFRACTION ( 1.90[Å] )
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