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<Asymmetric unit>

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PDB ID1z1m  sequence information (FASTA format)   
DescriptorUbiquitin-protein ligase E3 Mdm2 (E.C.6.3.2.-)
TitleNMR structure of unliganded MDM2
Functional Keywordspeptide-binding groove, psudosymmetry, alpha-beta domains, LIGASE
Biological sourceHomo sapiens (human)
Cellular location [UNP - Q00987] Nucleus, nucleoplasm
Organ source [UNP - Q00987] Colon
[UNP - Q00987] Ovarian carcinoma
[UNP - Q00987] Tongue
Total number of polymer chains1
Total molecular weight13571.7 (the details in Structural Details Page)
AuthorsUhrinova, S. , Uhrin, D. , Powers, H. , Watt, K. , Zheleva, D. , Fischer, P. , McInnes, C. , Barlow, P.N. (deposition date : 2005-03-04, release date : 2005-06-28)
Primary citationUhrinova, S. , Uhrin, D. , Powers, H. , Watt, K. , Zheleva, D. , Fischer, P. , McInnes, C. , Barlow, P.N.
Structure of Free MDM2 N-terminal Domain Reveals Conformational Adjustments that Accompany p53-binding
J.Mol.Biol., 350:587 - 598, 2005.(PubMed : 15953616)  (DOI: 10.1016/j.jmb.2005.05.010)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q00987 ) , eF-site , KEGG (EC 6.3.2.- ) , PISA , NRG-CING