PDB ID 1way sequence information (FASTA format)
RELATED PDB ID 1a2c , 1a3b , 1a3e , 1a46 , 1a4w , 1a5g , 1a61 , 1abi , 1abj , 1ad8 , 1ae8 , 1afe , 1aht , 1ai8 , 1aix , 1awf , 1awh , 1ay6 , 1b5g , 1b7x , 1ba8 , 1bb0 , 1bcu , 1bhx , 1bmm , 1bmn , 1bth , 1c1u , 1c1v , 1c1w , 1c4u , 1c4v , 1c4y , 1c5l , 1c5n , 1c5o , 1ca8 , 1d3d , 1d3p , 1d3q , 1d3t , 1d4p , 1d6w , 1d9i , 1de7 , 1dit , 1dm4 , 1doj , 1dwb , 1dwc , 1dwd , 1dwe , 1dx5 , 1e0f , 1eb1 , 1eoj , 1eol , 1fpc , 1fph , 1g30 , 1g32 , 1g37 , 1ghv , 1ghw , 1ghx , 1ghy , 1gj4 , 1gj5 , 1h8d , 1h8i , 1hag , 1hah , 1hai , 1hao , 1hap , 1hbt , 1hdt , 1hgt , 1hlt , 1hut , 1hxe , 1hxf , 1ihs , 1iht , 1jmo , 1jou , 1jwt , 1kts , 1ktt , 1lhc , 1lhd , 1lhe , 1lhf , 1lhg , 1mh0 , 1mu6 , 1mu8 , 1mue , 1nm6 , 1no9 , 1nrn , 1nro , 1nrp , 1nrq , 1nrr , 1nt1 , 1nu7 , 1nu9 , 1ny2 , 1nzq , 1o0d , 1o2g , 1o5g , 1ook , 1oyt , 1p8v , 1ppb , 1qbv , 1qhr , 1qj1 , 1qj6 , 1qj7 , 1qur , 1qvh , 1rd3 , 1riw , 1sb1 , 1sfq , 1sg8 , 1sgi , 1shh , 1sl3 , 1sr5 , 1ta2 , 1ta6 , 1tb6 , 1tbz , 1thp , 1thr , 1ths , 1tmb , 1tmt , 1tmu , 1tom , 1tq0 , 1tq7 , 1uma , 1uvs , 1vr1 , 1wbg , 2hgt , 2hnt , 2hpp , 2hpq , 2thf , 3htc , 4htc , 4thn , 5gds , 7kme , 8kme , 1k21 , 1k22 , 1nrs , 1vzq , 1w7g , 3hat
Descriptor THROMBIN LIGHT CHAIN (E.C.3.4.21.5), THROMBIN HEAVY CHAIN (E.C.3.4.21.5), HIRUGEN
Title ACTIVE SITE THROMBIN INHIBITORS
Functional Keywords PROTEASE, BLOOD COAGULATION, ACUTE PHASE, CALCIUM-BINDING, DIRECT PROTEIN SEQUENCING, DISEASE MUTATION, GAMMA-CARBOXYGLUTAMIC ACID, GLYCOPROTEIN, HYDROLASE, KRINGLE, PLASMA, POLYMORPHISM, SERINE PROTEASE, VITAMIN K
Biological source HOMO SAPIENS
(HUMAN)
Cellular location
[UNP - P00734 ]
Secreted, extracellular space
Organ source
[UNP - P00734 ]
BloodUNP - P00734 ]
Liver, and Mammary glandUNP - P00734 ]
LiverUNP - P00734 ]
UrineUNP - P00734 ]
Plasma
Total number of polymer chains 3
Total molecular weight 35736.5 (the details in Structural Details Page )
Authors Hartshorn, M.J. , Murray, C.W. , Cleasby, A. , Frederickson, M. , Tickle, I.J. , Jhoti, H.
(deposition date : 2004-10-28, release date : 2005-01-27)
Primary citation Hartshorn, M.J. , Murray, C.W. , Cleasby, A. , Frederickson, M. , Tickle, I.J. , Jhoti, H.J.Med.Chem. ,
48:403 - 413, 2005.(PubMed : 15658854) (DOI: 10.1021/jm0495778)
Experimental method X-RAY DIFFRACTION ( 2.02[Å] )
Other Database Information
