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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID1ttv  sequence information (FASTA format)   
RELATED PDB ID1ycq, 1rv1
DescriptorUbiquitin-protein ligase E3 Mdm2 (E.C.6.3.2.-)
TitleNMR Structure of a Complex Between MDM2 and a Small Molecule Inhibitor
Functional KeywordsMDM2, protein-protein interaction, LIGASE
Biological sourceXenopus laevis (African clawed frog)
Cellular location [UNP - P56273] Nucleus, nucleolus (By similarity)
Total number of polymer chains1
Total molecular weight12774.5 (the details in Structural Details Page)
AuthorsFry, D.C. , Emerson, S.D. , Palme, S. , Vu, B.T. , Liu, C.M. , Podlaski, F. (deposition date : 2004-06-23, release date : 2005-01-04)
Primary citationFry, D.C. , Emerson, S.D. , Palme, S. , Vu, B.T. , Liu, C.M. , Podlaski, F.
NMR structure of a complex between MDM2 and a small molecule inhibitor.
J.Biomol.Nmr, 30:163 - 173, 2004.(PubMed : 15557803)  (DOI: 10.1023/B:JNMR.0000048856.84603.9b)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P56273 ) , eF-site , KEGG (EC 6.3.2.- ) , PISA , NRG-CING