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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID1tz5  sequence information (FASTA format)   
RELATED PDB ID1ljv, 1f8p, 1tz4
DescriptorChimera of Pancreatic hormone and Neuropeptide Y
Title[pNPY19-23]-hPP bound to DPC Micelles
Functional KeywordsNPY-PP Chimera, HORMONE/GROWTH FACTOR COMPLEX
Biological sourceHomo sapiens, Sus scrofa (human, pig) (the details in Structural Details Page)
Cellular location [UNP - P01298] Secreted
Organ source [UNP - P01298] Pancreas
[UNP - P01298] Pancreatic tumor
[UNP - P01298] Pancreas, and Spleen
Total number of polymer chains1
Total molecular weight4277.9 (the details in Structural Details Page)
AuthorsLerch, M. , Kamimori, H. , Folkers, G. , Aguilar, M.I. , Beck-Sickinger, A.G. , Zerbe, O. (deposition date : 2004-07-09, release date : 2005-07-05)
Primary citationLerch, M. , Kamimori, H. , Folkers, G. , Aguilar, M.I. , Beck-Sickinger, A.G. , Zerbe, O.
Strongly Altered Receptor Binding Properties in PP and NPY Chimeras Are Accompanied by Changes in Structure and Membrane Binding
Biochemistry, 44:9255 - 9264, 2005.(PubMed : 15966750)  (DOI: 10.1021/bi0501232)
Experimental methodSOLUTION NMR
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01298, P01304 ) , eF-site , PISA , NRG-CING