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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID1uw3  sequence information (FASTA format)   
RELATED PDB ID1g04, 1m25
DescriptorPRION PROTEIN
TitleTHE CRYSTAL STRUCTURE OF THE GLOBULAR DOMAIN OF SHEEP PRION PROTEIN
Functional KeywordsTRANSMISSIBLE SPONGIFORM ENCEPHALOPATHY, CREUTZFELD JACOB DISEASE, PRION PROTEIN, SHEEP
Biological sourceOVIS ARIES (SHEEP)
Cellular location [UNP - P23907] Cell membrane; Lipid-anchor, GPI-anchor
Organ source [UNP - P23907] Spleen
[UNP - P23907] Brain
[UNP - P23907] Liver
[UNP - P23907] Epididymis
Total number of polymer chains1
Total molecular weight13012.4 (the details in Structural Details Page)
AuthorsHaire, L.F. , Whyte, S.M. , Vasisht, N. , Gill, A.C. , Verma, C. , Dodson, E.J. , Dodson, G.G. , Bayley, P.M. (deposition date : 2004-01-29, release date : 2004-03-25)
Primary citationHaire, L.F. , Whyte, S.M. , Vasisht, N. , Gill, A.C. , Verma, C. , Dodson, E.J. , Dodson, G.G. , Bayley, P.M.
The Crystal Structure of the Globular Domain of Sheep Prion Protein
J. Mol. Biol., 336:1175 - 1183, 2004.(PubMed : 15037077)  (DOI: 10.1016/J.JMB.2003.12.059)
Experimental methodX-RAY DIFFRACTION ( 2.05[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P23907 ) , eF-site , PISA