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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID1vkx  sequence information (FASTA format)   
DescriptorNF-KAPPA B P65 AND P50 SUBUNITS/DNA COMPLEX
TitleCRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
Functional KeywordsTRANSCRIPTION FACTOR, NF-KB, HETERODIMER, DNA-BINDING, TRANSCRIPTION/DNA COMPLEX
Biological sourceMus musculus (house mouse)
Cellular location [UNP - Q04207] Nucleus
[UNP - P25799] Nucleus. Isoform 5: Cytoplasm. Isoform 6: Nucleus. Isoform 7: Nucleus
Organ source [UNP - Q04207] Mammary gland
[UNP - P25799] Lung, and Spleen
[UNP - P25799] Spleen
[UNP - P25799] Embryo
[UNP - P25799] Lung carcinoma
[UNP - P25799] Inner ear, Kidney, and Spleen
Total number of polymer chains4
Total molecular weight73235.3 (the details in Structural Details Page)
AuthorsChen, F. , Huang, D.B. , Ghosh, G. (deposition date : 1997-09-17, release date : 1998-12-09)
Primary citationChen, F.E. , Huang, D.B. , Chen, Y.Q. , Ghosh, G.
Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA.
Nature, 391:410 - 413, 1998.(PubMed : 9450761)  (DOI: 10.1038/34956)
Experimental methodX-RAY DIFFRACTION ( 2.9[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q04207, P25799 ) , eF-site , PISA