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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID1y6o  sequence information (FASTA format)   
RELATED PDB ID1y6p, 1fxf, 1le6
DescriptorPhospholipase A2, major isoenzyme (E.C.3.1.1.4)
TitleCrystal structure of disulfide engineered porcine pancreatic phospholipase A2 to group-X isozyme in complex with inhibitor MJ33 and phosphate ions
Functional KeywordsHydrolase. Disulfide engineered PLA2. Porcine pancratic isozyme.
HYDROLASE
Biological sourceSus scrofa (pig)
Cellular location [UNP - P00592] Secreted
Organ source [UNP - P00592] Pancreas
Total number of polymer chains2
Total molecular weight31250.6 (the details in Structural Details Page)
AuthorsYu, B.Z. , Pan, Y.H. , Jassen, M.J.W. , Bahnson, B.J. , Jain, M.K. (deposition date : 2004-12-06, release date : 2005-03-22)
Primary citationYu, B.Z. , Pan, Y.H. , Janssen, M.J.W. , Bahnson, B.J. , Jain, M.K.
Kinetic and structural properties of disulfide engineered phospholipase a(2): insight into the role of disulfide bonding patterns.
Biochemistry, 44:3369 - 3379, 2005.(PubMed : 15736947)  (DOI: 10.1021/bi0482147)
Experimental methodX-RAY DIFFRACTION ( 2.00[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00592 ) , eF-site , KEGG ( EC 3.1.1.4 ) , PISA