PDB ID 1y8n sequence information (FASTA format)
RELATED PDB ID 1y8o , 1y8p
Descriptor [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 (E.C.2.7.1.99), Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (E.C.2.3.1.12)
Title Crystal structure of the PDK3-L2 complex
Functional Keywords pyruvate dehydrogenase kinase 3, lipoyl-bearing domain, protein-protein complex, TRANSFERASE
Biological source Homo sapiens
(human)
Cellular location
[UNP - Q15120 ]
Mitochondrion matrix
Organ source
[UNP - Q15120 ]
Liver
[UNP - Q15120 ]
Skin
[UNP - P10515 ]
Kidney
[UNP - P10515 ]
Placenta
Total number of polymer chains 2
Total molecular weight 62729.1 (the details in Structural Details Page )
Authors Kato, M. , Chuang, J.L. , Wynn, R.M. , Chuang, D.T.
(deposition date : 2004-12-13, release date : 2005-05-24)
Primary citation Kato, M. , Chuang, J.L. , Tso, S.C. , Wynn, R.M. , Chuang, D.T. Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex.
Embo J. ,
24:1763 - 1774, 2005.(PubMed : 15861126) (DOI: 10.1038/sj.emboj.7600663)
Experimental method X-RAY DIFFRACTION ( 2.60[Å] )
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