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PDB ID1vzc  sequence information (FASTA format)   
DescriptorTHYMIDYLATE SYNTHASE, 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE
TitleL. CASEI THYMIDYLATE SYNTHASE MUTANT E60Q BINARY COMPLEX WITH FDUMP
Functional KeywordsMETHYLTRANSFERASE, NUCLEOTIDE SYNTHASE
Biological sourceLactobacillus casei
Cellular location [UNP - P00469] Cytoplasm
Total number of polymer chains1
Total molecular weight36912.1 (the details in Structural Details Page)
AuthorsBirdsall, D.L. , Finer-Moore, J. , Stroud, R.M. (deposition date : 1996-09-18, release date : 1997-03-12)
Primary citationBirdsall, D.L. , Huang, W. , Santi, D.V. , Stroud, R.M. , Finer-Moore, J.
The separate effects of E60Q in Lactobacillus casei Thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis
Protein Eng., 11:171 - 183, 1998.(PubMed : 9613841)  (DOI: 10.1093/protein/11.3.171)
Experimental methodX-RAY DIFFRACTION ( 2.5[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P00469 ) , eF-site , KEGG ( EC 2.1.1.45 ) , PISA