PDB ID 1w8p sequence information (FASTA format)
RELATED PDB ID 1a7f , 1ai0 , 1aiy , 1b9e , 1ben , 1efe , 1ev3 , 1ev6 , 1evr , 1fu2 , 1fub , 1g7a , 1g7b , 1guj , 1hiq , 1his , 1hit , 1hls , 1htv , 1hui , 1iog , 1ioh , 1j73 , 1jca , 1jco , 1k3m , 1kmf , 1lkq , 1lnp , 1lph , 1mhi , 1mhj , 1mso , 1os3 , 1os4 , 1q4v , 1qiy , 1qiz , 1qj0 , 1sf1 , 1sjt , 1sju , 1t1k , 1t1p , 1t1q , 1trz , 1tyl , 1tym , 1uz9 , 1vkt , 1xda , 1xgl , 1zeg , 1zeh , 1znj , 2aiy , 2hiu , 3aiy , 4aiy , 5aiy
Descriptor INSULIN A-CHAIN, INSULIN B-CHAIN
Title STRUCTURAL PROPERTIES OF THE B25TYR-NME-B26PHE INSULIN MUTANT.
Functional Keywords INSULIN, IGF-1, X-RAY STRUCTURE, MUTANTS, HORMONE/GROWTH FACTOR
Biological source HOMO SAPIENS
Cellular location
[UNP - P01308 ]
Secreted
Organ source
[UNP - P01308 ]
Pancreas
[UNP - P01308 ]
Blood
Total number of polymer chains 12
Total molecular weight 35601.6 (the details in Structural Details Page )
Authors Zakowa, L. , Au-Alvarez, O. , Dodson, E.J. , Dodson, G.G. , Brzozowski, A.M.
(deposition date : 2004-09-24, release date : 2005-02-03)
Primary citation Zarkowa, L. , Brynda, J. , Au-Alvarez, O. , Dodson, E.J. , Dodson, G.G. , Whittingham, J.L. , Brzozowski, A.M. Towards the Insulin-Igf-I Intermediate Structures: Functional and Structural Properties of the B25Tyr-Nme-B26Phe Insulin Mutant.
Biochemistry ,
43:16293 - 16300, 2004.(PubMed : 15610023) (DOI: 10.1021/BI048856U)
Experimental method X-RAY DIFFRACTION ( 2.08[Å] )
Other Database Information