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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID1xlw  sequence information (FASTA format)   
RELATED PDB ID1poi, 1pom, 1pop, 1poq, 1xlu, 1xlv
DescriptorBUTYRYLCHOLINESTERASE (E.C.3.1.1.8)
TitleDiethylphosphorylated Butyrylcholinesterase (Nonaged) Obtained By Reaction With Echothiophate
Functional KeywordsCHOLINESTERASE; BChe, HYDROLASE
Biological sourceHomo sapiens (human)
Organ source [UNP - P06276] Fetus
[UNP - P06276] Brain
[UNP - P06276] Stomach
[UNP - P06276] Skin
[UNP - P06276] Plasma
Total number of polymer chains4
Total molecular weight62788 (the details in Structural Details Page)
AuthorsNachon, F. , Asojo, O.A. , Borgstahl, G.E.O. , Masson, P. , Lockridge, O. (deposition date : 2004-09-30, release date : 2005-02-01)
Primary citationNachon, F. , Asojo, O.A. , Borgstahl, G.E.O. , Masson, P. , Lockridge, O.
Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging
Biochemistry, 44:1154 - 1162, 2005.(PubMed : 15667209)  (DOI: 10.1021/bi048238d)
Experimental methodX-RAY DIFFRACTION ( 2.10[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P06276 ) , eF-site , KEGG ( EC 3.1.1.8 ) , PISA