English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID1xmy  sequence information (FASTA format)   
RELATED PDB ID1xlx, 1xlz, 1xm4, 1xm6, 1xmu, 1xn0, 1xom, 1xon, 1xoq, 1xor, 1xos, 1xot, 1xoz, 1xp0
DescriptorcAMP-specific 3',5'-cyclic phosphodiesterase 4B (E.C.3.1.4.17)
TitleCatalytic Domain Of Human Phosphodiesterase 4B In Complex With (R)-Rolipram
Functional KeywordsPhosphodiesterase, PDE, PDE4B, Rolipram, (R)-Rolipram, HYDROLASE
Biological sourceHomo sapiens (human)
Organ source [UNP - Q07343] Brain
Total number of polymer chains2
Total molecular weight92345.6 (the details in Structural Details Page)
AuthorsCard, G.L. , England, B.P. , Suzuki, Y. , Fong, D. , Powell, B. , Lee, B. , Luu, C. , Tabrizizad, M. , Gillette, S. , Ibrahim, P.N. , Artis, D.R. , Bollag, G. , Milburn, M.V. , Kim, S.-H. , Schlessinger, J. , Zhang, K.Y.J. (deposition date : 2004-10-04, release date : 2004-12-14)
Primary citationCard, G.L. , England, B.P. , Suzuki, Y. , Fong, D. , Powell, B. , Lee, B. , Luu, C. , Tabrizizad, M. , Gillette, S. , Ibrahim, P.N. , Artis, D.R. , Bollag, G. , Milburn, M.V. , Kim, S.-H. , Schlessinger, J. , Zhang, K.Y.J.
Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases.
STRUCTURE, 12:2233 - 2247, 2004.(PubMed : 15576036)  (DOI: 10.1016/j.str.2004.10.004)
Experimental methodX-RAY DIFFRACTION ( 2.40[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q07343 ) , eF-site , KEGG ( EC 3.1.4.17 ) , PISA