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MineSummary [1xse]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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PDB ID1xse  sequence information (FASTA format)   
Descriptor11beta-hydroxysteroid dehydrogenase type 1
TitleCrystal Structure of Guinea Pig 11beta-Hydroxysteroid Dehydrogenase Type 1
Functional Keywords11BETA-HYDROXYSTEROID DEHYDROGENASE DIMER, OXIDOREDUCTASE
Biological sourceCavia porcellus (domestic guinea pig)
Cellular location [UNP - Q6QLL4] Endoplasmic reticulum membrane; Single-pass type II membrane protein
Organ source [UNP - Q6QLL4] Liver
Total number of polymer chains2
Total molecular weight66168 (the details in Structural Details Page)
AuthorsOgg, D. , Elleby, B. , Norstrom, C. , Stefansson, K. , Abrahmsen, L. , Oppermann, U. , Svensson, S. (deposition date : 2004-10-19, release date : 2004-11-16)
Primary citationOgg, D. , Elleby, B. , Norstrom, C. , Stefansson, K. , Abrahmsen, L. , Oppermann, U. , Svensson, S.
The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions
J.Biol.Chem., 280:3789 - 3794, 2005.(PubMed : 15542590)  (DOI: 10.1074/jbc.M412463200)
Experimental methodX-RAY DIFFRACTION ( 2.50[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q6QLL4 ) , eF-site , KEGG ( EC 1.1.1.146 ) , PISA