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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID1a27  sequence information (FASTA format)   
Descriptor17-BETA-HYDROXYSTEROID-DEHYDROGENASE, ESTRADIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
TitleHUMAN 17-BETA-HYDROXYSTEROID-DEHYDROGENASE TYPE 1 C-TERMINAL DELETION MUTANT COMPLEXED WITH ESTRADIOL AND NADP+
Functional KeywordsDEHYDROGENASE, 17-BETA-HYDROXYSTEROID, MUTANT, ESTRADIOL, NADP
Biological sourceHomo sapiens (human)
Cellular locationCYTOPLASM
Organ source [UNP - P14061] Placenta
[UNP - P14061] Brain
Total number of polymer chains1
Total molecular weight32489.4 (the details in Structural Details Page)
AuthorsMazza, C. , Breton, R. , Housset, D. , Fontecilla-Camps, J.-C. (deposition date : 1998-01-16, release date : 1998-05-27)
Primary citationMazza, C.
Human Type I 17Beta-Hydroxysteroid Dehydrogenase: Site Directed Mutagenesis and X-Ray Crystallography Structure-Function Analysis
Thesis, Universite Joseph Fourier, : - , 1997.
Experimental methodX-RAY DIFFRACTION ( 1.9[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P14061 ) , eF-site , KEGG ( EC 1.1.1.62 ) , PISA