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<Asymmetric unit>
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PDB ID2isp  sequence information (FASTA format)   
RELATED PDB ID2iso
DescriptorPolymerase (DNA directed), beta/DNA Complex, 2'-DEOXY-5'-O-(HYDROXY{[HYDROXY(PHOSPHONOMETHYL)PHOSPHORYL]OXY}PHOSPHORYL)GUANOSINE
TitleTernary complex of DNA Polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-methylene triphosphate
Functional Keywordsnucleotidyl transferase, DNA polymerase, leaving-group, TRANSFERASE/DNA COMPLEX
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total molecular weight48428.3 (the details in Structural Details Page)
AuthorsSucato, C.A. , Upton, T.G. , Kashemirov, B.A. , Martinek, V. , Xiang, Y. , Beard, W.A. (deposition date : 2006-10-18, release date : 2007-01-30)
Primary citationSucato, C.A. , Upton, T.G. , Kashemirov, B.A. , Batra, V.K. , Martinek, V. , Xiang, Y. , Beard, W.A. , Pedersen, L.C. , Wilson, S.H. , McKenna, C.E. , Florian, J. , Warshel, A. , Goodman, M.F.
Modifying the beta,gamma Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase beta.
Biochemistry, 46:461 - 471, 2007.(PubMed : 17209556)  (DOI: 10.1021/bi061517b)
Experimental methodX-RAY DIFFRACTION ( 2.20[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P06746 ) , eF-site , PISA