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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID2oat  sequence information (FASTA format)   
DescriptorORNITHINE AMINOTRANSFERASE, 1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE
TitleORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE
Functional KeywordsAMINOTRANSFERASE, 5-FLUOROMETHYLORNITHINE, PLP-DEPENDENT ENZYME, PYRIDOXAL PHOSPHATE
Biological sourceHomo sapiens (human)
Cellular locationINTRAMITOCHONDRIA
Organ sourceLIVER
Total number of polymer chains3
Total molecular weight146905.5 (the details in Structural Details Page)
AuthorsStorici, P. , Schirmer, T. (deposition date : 1998-05-07, release date : 1998-12-09)
Primary citationStorici, P. , Capitani, G. , Muller, R. , Schirmer, T. , Jansonius, J.N.
Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine.
J. Mol. Biol., 285:297 - 309, 1999.(PubMed : 9878407)  (DOI: 10.1006/jmbi.1998.2289)
Experimental methodX-RAY DIFFRACTION ( 1.95[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P04181 ) , eF-site , KEGG ( EC 2.6.1.13 ) , PISA