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<Asymmetric unit>

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<Biological unit>
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PDB ID1zeh  sequence information (FASTA format)   
DescriptorINSULIN, M-CRESOL
TitleSTRUCTURE OF INSULIN
Functional KeywordsHORMONE, METABOLIC ROLE, CHEMICAL ACTIVITY, INSULIN MUTANT, CROSS-LINK, GLUCOSE METABOLISM, DIABETES
Biological sourceHomo sapiens (human)
Cellular location [UNP - P01308] Secreted
Organ source [UNP - P01308] Pancreas
[UNP - P01308] Blood
Total number of polymer chains4
Total molecular weight12413.7 (the details in Structural Details Page)
AuthorsWhittingham, J.L. , Edwards, E.J. , Antson, A.A. , Clarkson, J.M. , Dodson, G.G. (deposition date : 1998-05-01, release date : 1998-12-09)
Primary citationWhittingham, J.L. , Edwards, D.J. , Antson, A.A. , Clarkson, J.M. , Dodson, G.G.
Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry, 37:11516 - 11523, 1998.(PubMed : 9708987)  (DOI: 10.1021/bi980807s)
Experimental methodX-RAY DIFFRACTION ( 1.5[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01308 ) , eF-site , PISA