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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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( jV3 / Jmol ) *1
PDB ID2rhr  sequence information (FASTA format)   
RELATED PDB ID1x7h, 1x7g, 2rh4, 2rhc
DescriptorActinorhodin Polyketide Ketoreductase (E.C.1.3.1.-)
TitleP94L actinorhodin ketordeuctase mutant, with NADPH and Inhibitor Emodin
Functional Keywordsoxidoreductase, polyketide, actinorhodin, ketoreductase, combinatorial biosynthesis, short chain dehydrogenase/reductase
OXIDOREDUCTASE
Biological sourceStreptomyces coelicolor
Total number of polymer chains2
Total molecular weight60263.6 (the details in Structural Details Page)
AuthorsKorman, T.P. , Tsai, S.-C. (deposition date : 2007-10-09, release date : 2008-08-19)
Primary citationKorman, T.P. , Tan, Y.H. , Wong, J. , Luo, R. , Tsai, S.-C.
Inhibition kinetics and emodin cocrystal structure of a type II polyketide ketoreductase
Biochemistry, 47:1837 - 1847, 2008.(PubMed : 18205400)  (DOI: 10.1021/bi7016427)
Experimental methodX-RAY DIFFRACTION ( 2.500[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P16544 ) , eF-site , KEGG (EC 1.3.1.- ) , PISA