PDB ID 2od3 sequence information (FASTA format)
RELATED PDB ID 1shh
Descriptor Thrombin light chain, Thrombin heavy chain
Title Human thrombin chimera with human residues 184a, 186, 186a, 186b, 186c and 222 replaced by murine thrombin equivalents.
Functional Keywords SERINE PROTEASE, HYDROLASE
Biological source Homo sapiens
(human)
Cellular location
[UNP - P00734 ]
Secreted, extracellular space
Organ source
[UNP - P00734 ]
Mammary glandUNP - P00734 ]
Plasma
Total number of polymer chains 3
Total molecular weight 34543.9 (the details in Structural Details Page )
Authors Marino, F. , Chen, Z. , Ergenekan, C.E. , Bush, L.A. , Mathews, F.S. , Di Cera, E.
(deposition date : 2006-12-21, release date : 2007-04-10)
Primary citation Marino, F. , Chen, Z.W. , Ergenekan, C.E. , Bush-Pelc, L.A. , Mathews, F.S. , Di Cera, E.J.Biol.Chem. ,
282:16355 - 16361, 2007.(PubMed : 17428793) (DOI: 10.1074/jbc.M701323200)
Experimental method X-RAY DIFFRACTION ( 1.75[Å] )
Other Database Information
