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MineSummary [2ags]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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PDB ID2ags  sequence information (FASTA format)   
RELATED PDB ID1n1s, 2a75
Descriptorsialidase (E.C.3.2.1.18)
TitleTrypanosoma rangeli Sialidase in Complex with 2-Keto-3-deoxy-D-glycero-D-galacto-2,3-difluoro-nononic acid (2,3-difluoro-KDN)
Functional Keywordsbeta-propeller, covalent enzyme-intermediate complex, beta-sandwich, HYDROLASE
Biological sourceTrypanosoma rangeli
Total number of polymer chains1
Total molecular weight71668.3 (the details in Structural Details Page)
AuthorsAmaya, M.F. , Alzari, P.M. , Buschiazzo, A. (deposition date : 2005-07-27, release date : 2005-11-22)
Primary citationWatts, A.G. , Oppezzo, P. , Withers, S.G. , Alzari, P.M. , Buschiazzo, A.
Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.
J.Biol.Chem., 281:4149 - 4155, 2006.(PubMed : 16298994)  (DOI: 10.1074/jbc.M510677200)
Experimental methodX-RAY DIFFRACTION ( 1.700[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( O44049 ) , eF-site , KEGG ( EC 3.2.1.18 ) , PISA