PDB ID 2ath sequence information (FASTA format)
Descriptor Peroxisome proliferator activated receptor gamma
Title Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist
Functional Keywords PPAR, TRANSCRIPTION
Biological source Homo sapiens
(human)
Cellular location
[UNP - P37231 ]
Nucleus
Organ source
[UNP - P37231 ]
HeartUNP - P37231 ]
Adipose tissueUNP - P37231 ]
Bone marrowUNP - P37231 ]
Placenta
Total number of polymer chains 2
Total molecular weight 62947.6 (the details in Structural Details Page )
Authors Mahindroo, N. , Huang, C.-F. , Wu, S.-Y. , Hsieh, H.-P.
(deposition date : 2005-08-25, release date : 2006-08-25)
Primary citation Mahindroo, N. , Huang, C.-F. , Peng, Y.-H. , Wang, C.-C. , Liao, C.-C. , Lien, T.-W. , Chittimalla, S.K. , Huang, W.-J. , Chai, C.-H. , Prakash, E. , Chen, C.-P. , Hsu, T.-A. , Peng, C.-H. , Lu, I.-L. , Lee, L.-H. , Chang, Y.-W. , Chen, W.-C. , Chou, Y.-C. , Chen, C.-T. , Goparaju, C.M.V. , Chen, Y.-S. , Lan, S.-J. , Yu, M.-C. , Chen, X. , Chao, Y.-S. , Wu, S.-Y. , Hsieh, H.-P.J.Med.Chem. ,
48:8194 - 8208, 2005.(PubMed : 16366601) (DOI: 10.1021/jm0506930)
Experimental method X-RAY DIFFRACTION ( 2.28[Å] )
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