PDB ID 2bdl sequence information (FASTA format)
Descriptor Cathepsin K (E.C.3.4.22.38)
Title Cathepsin K complexed with a pyrrolidine ketoamide-based inhibitor
Functional Keywords cathepsin, cysteine protease, catK, catO, HYDROLASE
Biological source Homo sapiens
(human)
Cellular location
[UNP - P43235 ]
Lysosome
Organ source
[UNP - P43235 ]
BloodUNP - P43235 ]
BoneUNP - P43235 ]
OsteoclastomaUNP - P43235 ]
SpleenUNP - P43235 ]
Skin
Total number of polymer chains 1
Total molecular weight 24067.3 (the details in Structural Details Page )
Authors Shewchuk, L.M.
(deposition date : 2005-10-20, release date : 2006-03-21)
Primary citation Barrett, D.G. , Catalano, J.G. , Deaton, D.N. , Hassell, A.M. , Long, S.T. , Miller, A.B. , Miller, L.R. , Ray, J.A. , Samano, V. , Shewchuk, L.M. , Wells-Knecht, K.J. , Willard Jr., D.H. , Wright, L.L.Bioorg.Med.Chem.Lett. ,
16:1735 - 1739, 2006.(PubMed : 16376075) (DOI: 10.1016/j.bmcl.2005.11.101)
Experimental method X-RAY DIFFRACTION ( 2.0[Å] )
Other Database Information
