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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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PDB ID2cdz  sequence information (FASTA format)   
RELATED PDB ID2bva
DescriptorSERINE/THREONINE-PROTEIN KINASE PAK 4 (E.C.2.7.1.37)
TitleCRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 4 IN COMPLEX WITH CGP74514A
Functional KeywordsTRANSFERASE, PROTEIN KINASE, STE20, PAK4, ATP-BINDING
Biological sourceHOMO SAPIENS (HUMAN)
Organ source [UNP - O96013] Lymphoma
[UNP - O96013] Neuroblastoma
[UNP - O96013] Brain
[UNP - O96013] Eye, Pancreas, and Placenta
[UNP - O96013] Teratocarcinoma
[UNP - O96013] Epithelium
Total number of polymer chains1
Total molecular weight34849.6 (the details in Structural Details Page)
AuthorsDebreczeni, J.E. , Ugochukwu, E. , Eswaran, J. , Filippakopoulos, P. , Das, S. , Fedorov, O. , Sundstrom, M. , Arrowsmith, C. , Weigelt, J. , Edwards, A. , Von Delft, F. , Knapp, S. (deposition date : 2006-01-31, release date : 2006-02-08)
Primary citationEswaran, J. , Lee, W.H. , Debreczeni, J.E. , Filippakopoulos, P. , Turnbull, A. , Fedorov, O. , Deacon, S.W. , Peterson, J.R. , Knapp, S.
Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks.
Structure, 15:201 - , 2007.(PubMed : 17292838)  (DOI: 10.1016/j.str.2007.01.001)
Experimental methodX-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( O96013 ) , eF-site , KEGG ( EC 2.7.1.37 ) , PISA