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Summary [1k3m]

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PDB ID or Keywordsequenceauthor name

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PDB ID 1k3m  sequence information (FASTA format)    Descriptor INSULIN Title NMR STRUCTURE OF HUMAN INSULIN MUTANT ILE-A2-ALA, HIS-B10-ASP, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES Functional Keywords HORMONE, HUMAN INSULIN, MUTANT, HORMONE/GROWTH FACTOR COMPLEX Biological source [UNP - P01308] Homo sapiens (Human) Cellular location [UNP - P01308] Secreted Organ source [UNP - P01308] Pancreas [UNP - P01308] Blood Total number of polymer chains 2 Total molecular weight 5752.5 (the details in Structural Details Page) Authors Xu, B. , Hua, Q.-X. , Nakagawa, S.H. , Jia, W. , Chu, Y.-C. , Katsoyannis, P.G. , Weiss, M.A. (deposition date : 2001-10-03, release date : 2001-10-17) Primary citation Xu, B. , Hua, Q.X. , Nakagawa, S.H. , Jia, W. , Chu, Y.C. , Katsoyannis, P.G. , Weiss, M.A. A cavity-forming mutation in insulin induces segmental unfolding of a surrounding alpha-helix. Protein Sci., 11:104 - 116, 2002.(PubMed : 11742127)  (DOI: 10.1110/ps.ps.32102) Experimental method SOLUTION NMR Other Database Information EM Navigator , Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P01308 ) , eF-site , GDB , ProTherm , EzCatDB , PISA , PQS , NRG-CING

Electron density map is available to be displayed.

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