English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID2etm  sequence information (FASTA format)   
DescriptorFocal adhesion kinase 1 (E.C.2.7.1.112)
TitleCrystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative
Functional Keywordskinase catalytic domain, TRANSFERASE
Biological sourceHomo sapiens (human)
Cellular location [UNP - Q05397] Cell junction, focal adhesion
Organ source [UNP - Q05397] T-cell
[UNP - Q05397] Brain
[UNP - Q05397] Osteosarcoma
[UNP - Q05397] Melanocyte
[UNP - Q05397] Epithelium
Total number of polymer chains2
Total molecular weight65217.6 (the details in Structural Details Page)
AuthorsLee, C.C. (deposition date : 2005-10-27, release date : 2006-10-10)
Primary citationAndersen, C.B. , Ng, K. , Vu, C. , Ficarro, S. , Choi, H.-S. , Gray, N. , He, Y. , Lee, C.C.
Crystal Structure of Focal Adhesion Kinase Domain Complexed with ATP and novel 7H-Pyrrolo [2,3-d] pyrimidine scaffolds
To be Published, : - , .
Experimental methodX-RAY DIFFRACTION ( 2.3[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( Q05397 ) , eF-site , KEGG ( EC 2.7.1.112 ) , PISA