PDB ID 2fma sequence information (FASTA format)
RELATED PDB ID 1owt , 2fjz , 2fk1 , 2fk2 , 2fk3 , 2fkl
Descriptor Amyloid beta A4 protein precursor
Title Structure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, atomic resolution
Functional Keywords Alpha-Beta Two-layered Sandwich, METAL BINDING PROTEIN
Biological source Homo sapiens
(human)
Cellular location
[UNP - P05067 ]
Membrane; Single-pass type I membrane protein
Organ source
[UNP - P05067 ]
Brain
[UNP - P05067 ]
Leukocyte
[UNP - P05067 ]
Cerebellum
[UNP - P05067 ]
Eye, and Pancreas
[UNP - P05067 ]
Liver
[UNP - P05067 ]
Fibroblast
[UNP - P05067 ]
Platelet
[UNP - P05067 ]
Brain cortex
[UNP - P05067 ]
Blood vessel
[UNP - P05067 ]
Cerebrospinal fluid
[UNP - P05067 ]
Fetal brain
[UNP - P05067 ]
Plasma
[UNP - P05067 ]
Mammary epithelium
Total number of polymer chains 1
Total molecular weight 6941.1 (the details in Structural Details Page )
Authors Kong, G.K.-W.
(deposition date : 2006-01-08, release date : 2007-01-16)
Primary citation Kong, G.K. , Adams, J.J. , Cappai, R. , Parker, M.W. Structure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolution.
Acta Crystallogr.,Sect.F ,
63:819 - 824, 2007.(PubMed : 17909280) (DOI: 10.1107/S1744309107041139)
Experimental method X-RAY DIFFRACTION ( 0.85[Å] )
Other Database Information