English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID2fma  sequence information (FASTA format)   
RELATED PDB ID1owt, 2fjz, 2fk1, 2fk2, 2fk3, 2fkl
DescriptorAmyloid beta A4 protein precursor
TitleStructure of the Alzheimer's Amyloid Precursor Protein (APP) Copper Binding Domain in 'small unit cell' form, atomic resolution
Functional KeywordsAlpha-Beta Two-layered Sandwich, METAL BINDING PROTEIN
Biological sourceHomo sapiens (human)
Cellular location [UNP - P05067] Membrane; Single-pass type I membrane protein
Organ source [UNP - P05067] Brain
[UNP - P05067] Leukocyte
[UNP - P05067] Cerebellum
[UNP - P05067] Eye, and Pancreas
[UNP - P05067] Liver
[UNP - P05067] Fibroblast
[UNP - P05067] Platelet
[UNP - P05067] Brain cortex
[UNP - P05067] Blood vessel
[UNP - P05067] Cerebrospinal fluid
[UNP - P05067] Fetal brain
[UNP - P05067] Plasma
[UNP - P05067] Mammary epithelium
Total number of polymer chains1
Total molecular weight6941.1 (the details in Structural Details Page)
AuthorsKong, G.K.-W. (deposition date : 2006-01-08, release date : 2007-01-16)
Primary citationKong, G.K. , Adams, J.J. , Cappai, R. , Parker, M.W.
Structure of Alzheimer's disease amyloid precursor protein copper-binding domain at atomic resolution.
Acta Crystallogr.,Sect.F, 63:819 - 824, 2007.(PubMed : 17909280)  (DOI: 10.1107/S1744309107041139)
Experimental methodX-RAY DIFFRACTION ( 0.85[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P05067 ) , eF-site , PISA