English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID2z3q  sequence information (FASTA format)   
RELATED PDB ID2z3r
DescriptorInterleukin-15, Interleukin-15 receptor alpha chain
TitleCrystal structure of the IL-15/IL-15Ra complex
Functional KeywordsProtein-Protein complex, CYTOKINE/CYTOKINE RECEPTOR COMPLEX
Biological sourceHomo sapiens (human)
Cellular location [UNP - P40933] Isoform IL15-S48AA: Secreted. Isoform IL15-S21AA: Cytoplasm
[UNP - Q13261] Membrane; Single-pass type I membrane protein. Isoform 6: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Isoform 7: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Isoform 8: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Isoform 9: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Soluble interleukin-15 receptor subunit alpha: Secreted, extracellular space
Organ source [UNP - P40933] Bone marrow
[UNP - P40933] Lung cancer
[UNP - P40933] Testis
[UNP - P40933] Colon
[UNP - P40933] Epidermis
[UNP - Q13261] Bone marrow stroma
[UNP - Q13261] Brain
Total number of polymer chains4
Total molecular weight49508.6 (the details in Structural Details Page)
AuthorsChirifu, M. , Yamagata, Y. , Davis, S.J. , Ikemizu, S. (deposition date : 2007-06-05, release date : 2007-09-04)
Primary citationChirifu, M. , Hayashi, C. , Nakamura, T. , Toma, S. , Shuto, T. , Kai, H. , Yamagata, Y. , Davis, S.J. , Ikemizu, S.
Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans
Nat.Immunol., 8:1001 - 1007, 2007.(PubMed : 17643103)  (DOI: 10.1038/ni1492)
Experimental methodX-RAY DIFFRACTION ( 1.85[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P40933, Q13261 ) , eF-site , PISA