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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>

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PDB ID2fzc  sequence information (FASTA format)   
RELATED PDB ID1za1, 1za2, 2fzg, 2fzk
DescriptorAspartate carbamoyltransferase catalytic chain (E.C.2.1.3.2), Aspartate carbamoyltransferase regulatory chain (E.C.2.1.3.2)
TitleThe Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.10 Resolution
Functional KeywordsInhibitors, allosteric transition, Xray Structures, Transferase
Biological sourceEscherichia coli
Total number of polymer chains4
Total molecular weight104667.8 (the details in Structural Details Page)
AuthorsHeng, S. , Stieglitz, K.A. , Eldo, J. , Xia, J. , Cardia, J.P. , Kantrowitz, E.R. (deposition date : 2006-02-09, release date : 2006-08-29)
Primary citationHeng, S. , Stieglitz, K.A. , Eldo, J. , Xia, J. , Cardia, J.P. , Kantrowitz, E.R.
T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry, 45:10062 - 10071, 2006.(PubMed : 16906764)  (DOI: 10.1021/bi0601095)
Experimental methodX-RAY DIFFRACTION ( 2.10[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P0A786, P0A7F3 ) , eF-site , KEGG ( EC 2.1.3.2 ) , PISA