PDB ID 2fzc sequence information (FASTA format)
RELATED PDB ID 1za1 , 1za2 , 2fzg , 2fzk
Descriptor Aspartate carbamoyltransferase catalytic chain (E.C.2.1.3.2), Aspartate carbamoyltransferase regulatory chain (E.C.2.1.3.2)
Title The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.10 Resolution
Functional Keywords Inhibitors, allosteric transition, Xray Structures, Transferase
Biological source Escherichia coli
Total number of polymer chains 4
Total molecular weight 104667.8 (the details in Structural Details Page )
Authors Heng, S. , Stieglitz, K.A. , Eldo, J. , Xia, J. , Cardia, J.P. , Kantrowitz, E.R.
(deposition date : 2006-02-09, release date : 2006-08-29)
Primary citation Heng, S. , Stieglitz, K.A. , Eldo, J. , Xia, J. , Cardia, J.P. , Kantrowitz, E.R. T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry ,
45:10062 - 10071, 2006.(PubMed : 16906764) (DOI: 10.1021/bi0601095)
Experimental method X-RAY DIFFRACTION ( 2.10[Å] )
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