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MineSummary [2geq]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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PDB ID2geq  sequence information (FASTA format)   
DescriptorCellular tumor antigen p53/DNA Complex
TitleCrystal Structure of a p53 Core Dimer Bound to DNA
Functional KeywordsPROTEIN-DNA COMPLEX, Tumor Suppressor, TRANSCRIPTION/DNA COMPLEX
Biological sourceMus musculus (house mouse)
Cellular location [UNP - P02340] Cytoplasm (By similarity)
Organ source [UNP - P02340] Mammary carcinoma
[UNP - P02340] Lung fibroblast
[UNP - P02340] Mammary gland
Total number of polymer chains4
Total molecular weight55801.8 (the details in Structural Details Page)
AuthorsHo, W.C. , Fitzgerald, M.X. , Marmorstein, R. (deposition date : 2006-03-20, release date : 2006-05-23)
Primary citationHo, W.C. , Fitzgerald, M.X. , Marmorstein, R.
Structure of the p53 Core Domain Dimer Bound to DNA.
J.Biol.Chem., 281:20494 - 20502, 2006.(PubMed : 16717092)  (DOI: 10.1074/jbc.M603634200)
Experimental methodX-RAY DIFFRACTION ( 2.300[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P02340 ) , eF-site , PISA