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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID2hpb  sequence information (FASTA format)   
RELATED PDB ID1k4f, 2hp5, 2hp6, 2hp9
DescriptorBeta-lactamase PSE-2 (E.C.3.5.2.6)
TitleCrystal structure of the OXA-10 W154A mutant at pH 9.0
Functional Keywordsclass D beta-lactamase, lysine carboxylation, HYDROLASE
Biological sourcePseudomonas aeruginosa
Total number of polymer chains2
Total molecular weight55675.7 (the details in Structural Details Page)
AuthorsKerff, F. , Falzone, C. , Herman, R. , Sauvage, E. , Charlier, P. (deposition date : 2006-07-17, release date : 2007-07-03)
Primary citationBaurin, S. , Vercheval, L. , Bouillenne, F. , Falzone, C. , Brans, A. , Jacquamet, L. , Ferrer, J.L. , Sauvage, E. , Dehareng, D. , Frere, J.M. , Charlier, P. , Galleni, M. , Kerff, F.
Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.
Biochemistry, 48:11252 - 11263, 2009.(PubMed : 19860471)  (DOI: 10.1021/bi901548c)
Experimental methodX-RAY DIFFRACTION ( 2.05[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P14489 ) , eF-site , KEGG ( EC 3.5.2.6 ) , PISA