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MineSummary [2jgi]

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>

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PDB ID2jgi  sequence information (FASTA format)   
RELATED PDB ID1c2b, 1c2o, 1j06, 1j07, 1ku6, 1maa, 1mah, 1n5m, 1n5r, 1q83, 1q84, 2c0p, 2c0q, 2h9y, 2ha0, 2ha2, 2ha3, 2ha4, 2ha5, 2ha6, 2ha7, 2jey, 2jez, 2jf0, 2jge, 2jgf, 2jgj, 2jgk, 2jgl, 2jgm, 2jgg, 2jgh
DescriptorACETYLCHOLINESTERASE (E.C.3.1.1.7)
TitleCRYSTAL STRUCTURE OF MOUSE ACETYLCHOLINESTERASE INHIBITED BY NON-AGED DIISOPROPYL FLUOROPHOSPHATE (DFP)
Functional KeywordsDFP, SYNAPSE, MEMBRANE, HYDROLASE, GLYCOPROTEIN, SERINE ESTERASE, ACETYLCHOLINESTERASE, NEUROTRANSMITTER DEGRADATION, ALTERNATIVE SPLICING, DIISOPROPYL FLUOROPHOSPHATE
Biological sourceMUS MUSCULUS (MOUSE)
Total number of polymer chains2
Total molecular weight121153 (the details in Structural Details Page)
AuthorsHornberg, A. , Tunemalm, A.-K. , Ekstrom, F. (deposition date : 2007-02-13, release date : 2007-04-17)
Primary citationHornberg, A. , Tunemalm, A.-K. , Ekstrom, F.
Crystal Structures of Acetylcholinesterase in Complex with Organophosphorus Compounds Suggest that the Acyl Pocket Modulates the Aging Reaction by Precluding the Formation of the Trigonal Bipyramidal Transition State.
Biochemistry, 46:4815 - , 2007.(PubMed : 17402711)  (DOI: 10.1021/BI0621361)
Experimental methodX-RAY DIFFRACTION ( 2.90[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P21836 ) , eF-site , KEGG ( EC 3.1.1.7 ) , PISA