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<Asymmetric unit>
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PDB ID1d5r  sequence information (FASTA format)   
DescriptorPROTEIN-TYROSINE PHOSPHOTASE PTEN (E.C.3.1.3.48)
TitleCrystal Structure of the PTEN Tumor Suppressor
Functional KeywordsC2 DOMAIN, PHOSPHOTIDYLINOSITOL, PHOSPHOTASE, HYDROLASE
Biological sourceHomo sapiens (human)
Cellular location [UNP - P60484] Cytoplasm
Organ source [UNP - P60484] Epithelium
[UNP - P60484] Lung
Total number of polymer chains1
Total molecular weight38646.6 (the details in Structural Details Page)
AuthorsLee, J.O. , Yang, H. , Georgescu, M.-M. , Di Cristofano, A. , Pavletich, N.P. (deposition date : 1999-10-11, release date : 1999-11-04)
Primary citationLee, J.O. , Yang, H. , Georgescu, M.M. , Di Cristofano, A. , Maehama, T. , Shi, Y. , Dixon, J.E. , Pandolfi, P. , Pavletich, N.P.
Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association.
Cell(Cambridge,Mass.), 99:323 - 334, 1999.(PubMed : 10555148)  (DOI: 10.1016/S0092-8674(00)81663-3)
Experimental methodX-RAY DIFFRACTION ( 2.1[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P60484 ) , eF-site , KEGG ( EC 3.1.3.48 ) , PISA