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MineSummary [2pd4]

[2pd4] replaced from '1jw7'

Summary Structural Experimental Function Sequence Neighbor Download Link

<Asymmetric unit>
= <Biological unit>

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PDB ID2pd4  sequence information (FASTA format)   
RELATED PDB ID2pd3
DescriptorEnoyl-[acyl-carrier-protein] reductase [NADH] (E.C.1.3.1.9)
TitleCrystal Structure of the Helicobacter pylori Enoyl-Acyl Carrier Protein Reductase in Complex with Hydroxydiphenyl Ether Compounds, Triclosan and Diclosan
Functional Keywordsantibacterial target, Helicobacter pylori, type II fatty acid biosynthesis, enoyl-ACP-reductase, fabI, OXIDOREDUCTASE
Biological sourceHelicobacter pylori
Cellular location [UNP - O24990] Cell inner membrane; Peripheral membrane protein (By similarity)
Total number of polymer chains4
Total molecular weight123740.4 (the details in Structural Details Page)
AuthorsLee, H.H. , Moon, J.H. , Suh, S.W. (deposition date : 2007-03-31, release date : 2007-04-17)
Primary citationLee, H.H. , Moon, J.H. , Suh, S.W.
Crystal structure of the Helicobacter pylori enoyl-acyl carrier protein reductase in complex with hydroxydiphenyl ether compounds, triclosan and diclosan
Proteins, 69:691 - 694, 2007.(PubMed : 17879346)  (DOI: 10.1002/prot.21586)
Experimental methodX-RAY DIFFRACTION ( 2.30[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( O24990 ) , eF-site , KEGG ( EC 1.3.1.9 ) , PISA