PDB ID 2osc sequence information (FASTA format)
RELATED PDB ID 2oo8
Descriptor Tie-2
Title Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors
Functional Keywords Kinase domain Tie-2, Transferase
Biological source Homo sapiens
(human)
Cellular location
[UNP - Q02763 ]
Membrane; Single-pass type I membrane protein
Organ source
[UNP - Q02763 ]
Placenta
Total number of polymer chains 1
Total molecular weight 36703 (the details in Structural Details Page )
Authors Bellon, S.F. , Kim, J.
(deposition date : 2007-02-05, release date : 2007-03-20)
Primary citation Hodous, B.L. , Geuns-Meyer, S.D. , Hughes, P.E. , Albrecht, B.K. , Bellon, S. , Caenepeel, S. , Cee, V.J. , Chaffee, S.C. , Emery, M. , Fretland, J. , Gallant, P. , Gu, Y. , Johnson, R.E. , Kim, J.L. , Long, A.M. , Morrison, M. , Olivieri, P.R. , Patel, V.F. , Polverino, A. , Rose, P. , Wang, L. , Zhao, H.Bioorg.Med.Chem.Lett. ,
17:2886 - 2889, 2007.(PubMed : 17350837) (DOI: 10.1016/j.bmcl.2007.02.067)
Experimental method X-RAY DIFFRACTION ( 2.8[Å] )
Other Database Information
