PDB ID 2q5s sequence information (FASTA format)
RELATED PDB ID 2q59 , 2q5p , 2q61 , 2q6r , 2q6s
Descriptor Peroxisome Proliferator-Activated Receptor gamma, ligand binding domain
Title Crystal Structure of PPARgamma bound to partial agonist nTZDpa
Functional Keywords Protein-ligand complex, Ligand binding protein
Biological source Homo sapiens
(human)
Cellular location
[UNP - P37231 ]
Nucleus
Organ source
[UNP - P37231 ]
Heart
[UNP - P37231 ]
Adipose tissue
[UNP - P37231 ]
Bone marrow
[UNP - P37231 ]
Placenta
Total number of polymer chains 2
Total molecular weight 63447.8 (the details in Structural Details Page )
Authors Bruning, J.B. , Nettles, K.W.
(deposition date : 2007-06-01, release date : 2007-10-23)
Primary citation Bruning, J.B. , Chalmers, M.J. , Prasad, S. , Busby, S.A. , Kamenecka, T.M. , He, Y. , Nettles, K.W. , Griffin, P.R. Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism
Structure ,
15:1258 - 1271, 2007.(PubMed : 17937915) (DOI: 10.1016/j.str.2007.07.014)
Experimental method X-RAY DIFFRACTION ( 2.050[Å] )
Other Database Information