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<Asymmetric unit>
= <Biological unit>

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PDB ID2qa6  sequence information (FASTA format)   
RELATED PDB ID2qa8, 2qab
DescriptorEstrogen receptor, nuclear receptor coactivator 2
TitleCrystal Structure of Estrogen Receptor Alpha mutant 537S Complexed with 4-(6-hydroxy-1H-indazol-3-yl)benzene-1,3-diol
Functional KeywordsProtein-Ligand Complex, TRANSCRIPTION
Biological sourceHomo sapiens (human)
Cellular location [UNP - P03372] Nucleus
Organ source [UNP - P03372] Mammary gland
[UNP - P03372] Mammary carcinoma
[UNP - Q8BN74] Eyeball
Total number of polymer chains4
Total molecular weight62417.8 (the details in Structural Details Page)
AuthorsNettles, K.W. , Bruning, J.B. , Nowak, J. , Sharma, S.K. , Hahm, J.B. , Shi, Y. , Kulp, K. , Hochberg, R.B. , Zhou, H. , Katzenellenbogen, J.A. , Katzenellenbogen, B.S. , Kim, Y. , Joachmiak, A. , Greene, G.L. (deposition date : 2007-06-14, release date : 2008-03-18)
Primary citationNettles, K.W. , Bruning, J.B. , Gil, G. , Nowak, J. , Sharma, S.K. , Hahm, J.B. , Kulp, K. , Hochberg, R.B. , Zhou, H. , Katzenellenbogen, J.A. , Katzenellenbogen, B.S. , Kim, Y. , Joachmiak, A. , Greene, G.L.
NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
Nat.Chem.Biol., 4:241 - 247, 2008.(PubMed : 18344977)  (DOI: 10.1038/nchembio.76)
Experimental methodX-RAY DIFFRACTION ( 2.600[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P03372, Q8BN74 ) , eF-site , PISA