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Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

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( jV3 / Jmol ) *1
PDB ID2qds  sequence information (FASTA format)   
RELATED PDB ID1x8g, 1x8i, 2gkl
DescriptorCRYSTAL STRUCTURE OF THE ZINC CARBAPENEMASE CPHA IN COMPLEX WITH THE INHIBITOR D-CAPTOPRIL
TitleCrystal Structure of the Zinc Carbapenemase CPHA in Complex with the Inhibitor D-Captopril
Functional KeywordsHYDROLASE, LACTAMASE, INHIBITOR, ZN, METAL
Biological sourceAeromonas hydrophila
Cellular location [UNP - P26918] Periplasm (Probable)
Total number of polymer chains1
Total molecular weight26072.3 (the details in Structural Details Page)
AuthorsGarau, G. , Dideberg, O. (deposition date : 2007-06-21, release date : 2007-07-17)
Primary citationLienard, B.M. , Garau, G. , Horsfall, L. , Karsisiotis, A.I. , Damblon, C. , Lassaux, P. , Papamicael, C. , Roberts, G.C. , Galleni, M. , Dideberg, O. , Frere, J.M. , Schofield, C.J.
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols.
Org.Biomol.Chem., 6:2282 - 2294, 2008.(PubMed : 18563261)  (DOI: 10.1039/b802311e)
Experimental methodX-RAY DIFFRACTION ( 1.66[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P26918 ) , eF-site , KEGG ( EC 3.5.2.6 ) , PISA