English Statistics Help FAQ Contact Us
Download >>

PDBj (Protein Data Bank Japan) maintains a centralized PDB archive of macromolecular structures and provides integrated tools, in collaboration with the RCSB, the BMRB in USA and the PDBe in EU. PDBj is supported by JST-NBDC and Osaka University.

Summary Structural Experimental Function Sequence Neighbor Download Link


<Asymmetric unit>
= <Biological unit>

More images...
View in 3D molecule viewer
( jV3 / Jmol ) *1
PDB ID2qns  sequence information (FASTA format)   
RELATED PDB ID2hlb, 1y3a, 1tbg, 1f88
DescriptorGuanine nucleotide-binding protein G(I)/G(S)/G(T) beta-1 subunit, Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, C-terminal Segment of the PTH1 Parathyroid Hormone Receptor
TitleCrystal Structure of the G-protein Betagamma Subunit Bound to a C-terminal Region of the PTH1 Parathyroid Hormone Receptor
Functional KeywordsG-protein, receptor, GPCR, WD40, peptide, betagamma, Acetylation, Transducer, WD repeat, Lipoprotein, Membrane, Phosphorylation, Prenylation, SIGNALING PROTEIN
Biological sourceHomo sapiens (human)
Cellular location [UNP - P59768] Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Organ source [UNP - P62873] Liver
[UNP - P62873] Brain, Muscle, and Uterus
[UNP - P62873] B-cell lymphoma, and Melanoma
[UNP - P62873] Ovarian carcinoma
[UNP - P62873] Fetal brain cortex
[UNP - P59768] Brain, and Skin
Total number of polymer chains3
Total molecular weight46503.8 (the details in Structural Details Page)
AuthorsJohnston, C.A. , Siderovski, D.P. (deposition date : 2007-07-19, release date : 2008-07-01)
Primary citationJohnston, C.A. , Kimple, A.J. , Giguere, P.M. , Siderovski, D.P.
Structure of the Parathyroid Hormone Receptor C Terminus Bound to the G-Protein Dimer Gbeta(1)gamma(2).
Structure, 16:1086 - 1094, 2008.(PubMed : 18611381)  (DOI: 10.1016/j.str.2008.04.010)
Experimental methodX-RAY DIFFRACTION ( 3.00[Å] )
Other Database Information
Yorodumi , CATH , CE , FSSP , SCOP , VAST , UniProt ( P62873, P59768 ) , eF-site , PISA